The PENELLOPE Large Programme (Pr.Id. 106.20Z8) is a multi-instrument spectroscopic survey aimed at obtaining complementary data to the targets of the ULLYSES program. The latter is a Hubble Space Telescope (HST) Director’s Discretionary Time that was executed in a three-year period, from HST Cycle 27 through Cycle 29 (2020-2022). The HST ULLYSES program is aimed at obtaining low- and medium-resolution spectra of young stars covering the wavelength range from ∼140 nm to ∼1 μm, hence providing a view of accretion and ejection tracers at ultraviolet wavelengths. The PENELLOPE program is a public community-driven effort. It provides optical high-resolution (ESPRESSO, UVES, R>60,000) and medium-resolution flux-calibrated optical and infrared spectra (up to 2.5 μm) with X-Shooter (R > 10,000), giving access to information that is otherwise not obtainable with the HST spectra provided by ULLYSES, such as main stellar properties, accurate interstellar extinction, and veiling; kinematics and geometry of the accretion and wind processes, and more.