Exoplanets have become central to astrophysics. The formation and evolution of exoplanets can now be explored with instrumentation and observational techniques covering multiple physical scales and wavelengths. The composition and substructures of planet-forming disks can be observed directly to witness and characterise young proto-planets in formation. Planetary atmospheres, architectures and demographics can be systematically scrutinised to refine our understanding of the physical processes at play in the formation of giant and terrestrial planets, and in favorable conditions for the emergence of life. ESO facilities provide access to a large part of the electromagnetic spectrum to probe cold and hot phases, dynamics and interactions, close and distant environments, and the relations with the host star. Observations with different ESO facilities have led to unique discoveries, e.g. the PDS 70 planetary system, and can successfully be used in synergy with space facilities, e.g. HST, CHEOPS, TESS, GAIA, JWST.